Patients with acute ischemic stroke are screened for in- and exclusion criteria when admitted to the hospital. Randomization takes place within 3 h when no acute recanalization measures take place or within 3 h after cessation of recanalization measures. From then on, monitoring and optimizing of hemodynamic parameters are applied for the next 48 h in both groups. Data of NIH-SS scores are collected on day 1, 2, 3, and 10 ± 3, the data of mRS scores at time of discharge and after 3 and 6 months. A follow-up MRI is performed on day 10 ± 3.
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