Abstracts and full texts were reviewed by two independent investigators (CF, FR, MT, RH and YS). Discrepancies were resolved by discussion. Non-English articles were assessed by native speakers with medical backgrounds. Data extraction items and strategies can be found in the online supplemental appendix. Pathogen and antibiotic resistance data were only considered from the year 2000 onwards. Authors were contacted to specify methods and to provide additional data. Studies that met the inclusion criteria were assessed for risk of bias by the Hoy tool.13
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