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2.3. Study endpoints
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The primary endpoint was OS. Secondary endpoints included progression-free survival (PFS), objective response rate (ORR) according to RECIST, grade 3 or greater adverse events according to National Cancer Institute Common Terminology Criteria for Adverse Events (G ≥ 3CTCAE). Exploratory endpoints include hypertension, hemorrhage, treatment-related deaths and total on-treatment deaths (G5 AE). Preplanned subgroup analyses of OS were conducted according to line of therapy, histology and chemotherapy partner.
Copyright and License information: ©2016
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