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Existing statistical methods of haplotype reconstruction

GK Gie Ken-Dror
PS Pankaj Sharma
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There are five other published methods that are available to use: MalHaploFreq software, Maximum likelihood (ML) estimation using a hill climbing algorithm [14] (hereon called “MHF”). Expectation–maximization (EM) algorithm malaria.em [15] estimation using efficient iterative maximum likelihood approach (hereon called “R-EM”. A Bayesian approach [17] estimation using a Metropolis–Hastings Markov chain Monte Carlo (hereon called “Bayesian”). Another expectation–maximization (EM) algorithm [16] estimation using maximum likelihood approach that incorporates MOI (hereon called “EM”). And the Markov chain Monte Carlo (MCMC)-algorithm [16] using acceptance/rejection algorithm (hereon called “MCMC”). Summary of the statistical methods for haplotype reconstruction presents in the Additional file 1: Table S1.1.

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