Seven heavy metals were measured: The concentrations of Pb in blood was analyzed using graphite furnace atomic absorption spectrometry (AA800, Perkin Elmer), and Cd, Ni, Cu, Cr, Mn, and As in urine were analyzed using inductively coupled plasma mass spectrometry (ICP-MS, NexION 300 Series, Perkin Elmer). Details of the instrumental analysis have been reported by a CAP (COLLEGE of AMERICAN PATHOLOGISTS) accredited clinical laboratory (Union clinical laboratory Taipei, Taiwan, CAP Number: 6979606). The capability of tests is monitored through regular routine daily internal quality control testing and external proficiency test.
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