Quality scores from the Mixed Methods Appraisal Tool (MMAT)67 will be used to assess the risk of bias as this tool accommodates quantitative, qualitative and mixed methods, so the same tool can be used for all studies. If appropriate, for systematic reviews, the MMAT will be supplemented by A Measurement Tool to Assess Systematic Reviews version 2.68 They will be applied by the reviewers (RG and LM) independently, and the results will be tabulated to enable easy comparison. Similarly, as with data extraction methodology, discrepancies will be discussed and a third reviewer (IM) will be consulted to resolve any disagreements.
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