Loss of righting reflex test

KI Koji Iwanaga
YS Yasushi Satoh
RA Ryosuke Akai
TI Toshiaki Ishizuka
TK Tomiei Kazama
TI Takehiko Ikeda
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Dose-dependency of JM-1232(−)’s sedative effects was evaluated by the LORR test48. Twenty minutes after the mouse received a single injection of anaesthetic, the animal was placed on its back gently and scored as LORR if it failed to completely right itself within 30 s. One trial was given.

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