4.3.3. Carrageenan-Induced Paw Edema

An amount of 0.1 mL of an aqueous carrageenan solution (1% w/v) was injected into the hind paw of adult Wistar rats (6 rats were used for each compound). The tested compounds (in water with a few drops of Tween 80) were administered i.p. (0.15 mmol/kg) 5 min before the carrageenan administration. The produced edema, after 3.5 h, was estimated as paw weight increase [32].