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Rotarod performance test

MK Murat Kirtay
JS Josefine Sell
CM Christian Marx
HH Holger Haselmann
MC Mihai Ceanga
ZZ Zhong-Wei Zhou
VR Vahid Rahmati
JK Joanna Kirkpatrick
KB Katrin Buder
PG Paulius Grigaravicius
AO Alessandro Ori
CG Christian Geis
ZW Zhao-Qi Wang
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Before the testing period, mice were trained for one day on the rotarod apparatus (Ugo Basile, Italy) at a constant speed (5 rpm) for a maximum of 5 min, to allow them adapt to the testing environment. During the testing period, each mouse was placed on the rotarod at an accelerated speed (20 rpm/min), from 4 to 40 rpm for a maximum of 200 s. When the mice fell, they were removed from the apparatus and placed back into their cage for at least 30 min to recover before the next trial. All mice experienced three trials per day for five consecutive days. Latency to fall served as an indicator of motor coordination.

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