Data Quality

The quality of data within the Research Registry^® was assessed using quality criteria that were developed alongside the registry. These are based on Sir Austin Bradford Hill’s criteria for what an account of a research study should convey (8), and each of the four key questions is linked directly to fields in the database (Table ​(Table1).1). Studies were scored out of nine using these quality criteria; receiving one point for each criterion met. Two teams of researchers (Christopher Limb/Mohammed Omer Anwar/Harkiran Sagoo and Yasser Al Omran/Kiron Koshy/Daniyal J. Jafree) scored each registration independently and compared results. Individual discrepancies in scoring were referred to the lead researcher for each group (Christopher Limb or Yasser Al Omran) for adjudication, and where consensus was not made, the decision was escalated to the lead author (Riaz Agha). The proportion of quality criteria met per registration was expressed as a percentage.

Quality indicator score for registrations.

Primary investigator

Participating institutions

Countries recruiting

Key questions and objectives

Patient population

Intervention

Control or comparator

Primary outcomes (and secondary if used)

Dates of enrollment