The percentages of patients who had total infusion durations of ≤ 2 or > 3.5 h were calculated. If a patient experienced multiple short infusions during one dose/the same day, the total duration is the sum of all records related to that dose. Infusion-rate distributions describing the protocol-recommended infusion rate (range 50–400 mg/h) and the theoretical highest infusion rate (using a cut-off of ≤ 760 mg/h, based on the highest dose in the study population) were summarized.
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