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MV Marie Viala
NF Nelly Firmin
CT Célia Touraine
SP Stéphane Pouderoux
MM Manon Metge
LR Lobna Rifai
GR Gilles Romieu
HF Hélène de Forges
LR Lise Roca
SG Séverine Guiu
VD Véronique D’Hondt
WJ William Jacot
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Inclusion criteria were: ≥18-year-old patients with EBC, with Eastern Cooperative Oncology Group (ECOG) score of 0 or 1, and programmed to receive six cycles of adjuvant chemotherapy. The main exclusion criteria were: metastatic disease, another cancer treated in the previous 3 years, contra-indication to calcium or cholecalciferol administration (severe allergic reactions to vitamin D or calcium supplementation or to excipients, diseases or conditions that cause hypercalcemia and/or hypercalciuria, calcium nephrolithiasis, tissue calcification, hypervitaminosis D), significant comorbidities (e.g. uncontrolled endocrine disease, pre-existing disorder in the phosphorus-calcium balance in the last 3 years, osteopenia or osteoporosis requiring treatment with calcium and vitamin D treatment), and any concomitant treatment with experimental products.

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