Protocol to request
            
                Isolation of biologically derived human Aβ and cellular assay for γ-secretase-mediated proteolysis
                
                
            
        
        
            
                Research article
            
            
                Alzheimer’s disease linked Aβ42 exerts product feedback inhibition on γ-secretase impairing downstream cell signaling
                
            
            
            
                Katarzyna Marta Zoltowska et al.
            
            
                DOI: 10.7554/eLife.90690