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ANGPTL4-mediated unfolding of LPL assessed by pulse-labeling HDX-MS
Research advance
The angiopoietin-like protein ANGPTL4 catalyzes unfolding of the hydrolase domain in lipoprotein lipase and the endothelial membrane protein GPIHBP1 counteracts this unfolding
Simon Mysling et al.
DOI: 10.7554/eLife.20958