Protocol to request
            
                Initial and final reproductive rates of an antigenic mutant evolving de novo from a resident viral population
                
                
            
        
        
            
                Research article
            
            
                The effects of a deleterious mutation load on patterns of influenza A/H3N2's antigenic evolution in humans
                
            
            
            
                Katia Koelle et al.
            
            
                DOI: 10.7554/eLife.07361