Protocol to request
Synthesis of GE-rifamycin bipartite inhibitor: step 3, synthesis of {[α-descarboxy-Ama]GE}-NH-{RifSV} (compound 3 of Figure 7C; “RifaGE-3”)
Research article
GE23077 binds to the RNA polymerase ‘i’ and ‘i+1’ sites and prevents the binding of initiating nucleotides
Yu Zhang et al.
DOI: 10.7554/eLife.02450