The two tests are used to evaluate in vivo sensitivity to insulin in mouse. The hypoerinsulinemic-euglycemic clamp provides information about the sensitivity to insulin in liver and other metabolically relevant tissues.
Paschos, G. K. and FitzGerald, G. A. (2013). Insulin Tolerance Test and Hyperinsulinemic-euglycemic Clamp. Bio-protocol 3(10): e776. DOI: 10.21769/BioProtoc.776.