Locomotor Coordination Assay in Rats
大鼠中运动器官协调性的试验
发布: 2015年11月20日第5卷第22期 DOI: 10.21769/BioProtoc.1655 浏览次数: 9611
评审: Soyun KimTifany DesprezAnonymous reviewer(s)
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参见作者原研究论文
The authors used this protocol in:
Apr 2015
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Abstract
Neonatal hypoxia-ischemia (HI) affects 60% of low birth weight infants and up to 40% of preterm births. Cell death and brain injury after HI have been shown to cause long-lasting neurological deficits. Two motor coordination tests on rats that had been exposed to HI on postnatal day 7 (P7) showed that HI in the P7 rat is associated with significant motor coordination impairment. These results call attention to the risks associated with perinatal ischemia and the need for proper treatment to reverse HI-induced deleterious effects.
Keywords: Motor coordination (运动协调)
Balance (平衡)
Inclined plane (斜面)
Rat (大鼠)
Hypoxia (缺氧)
Materials and Reagents
- Rats
Equipment
Note: Both rod and incline wire mesh are self-made from supplies bought at hardware store.
- Rod (30.0 cm L x 1.0 cm)
- Wire mesh (69.5 cm W x 45 cm L with 3 cm gaps)
Procedure
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文章信息
版权信息
© 2015 The Authors; exclusive licensee Bio-protocol LLC.
如何引用
Perez-Polo, J. R., Rea, H. C. and Infante, S. K. (2015). Locomotor Coordination Assay in Rats. Bio-protocol 5(22): e1655. DOI: 10.21769/BioProtoc.1655.
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分类
神经科学 > 行为神经科学 > 实验动物模型 > 大鼠
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