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Reverse compliment k-mer

NE Neda Emami
RF Reza Ferdousi
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The reverse complement of a DNA sequence is organized by replacing T and A, exchanging G and C, and reversing the letters. (See Fig. 5B) As an example, if k = 2 so there are 16 basic k-mers in total, but by reverse compliment k-mers, there are ten different k-mers. Therefore, the total possible number of reverse complement k-mer will be calculated as follows:

We set (k = 3, 4) for each aptamer, and as a result, each aptamer was encoded into a 44-dimensional vector for k = 3 and a 179-dimensional vector for k = 4. In this study, to generate characteristics of aptamers, we used a powerful python package known as RepDNA114.

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