For the swelling study, a one-tailed paired Student’s t test was used to determine whether an increase occurred from initial to equilibrium swelling ratio for each hydrogel formulation. For GPC data, a two-tailed paired Student’s t test was used to identify whether changes in Mn and PDI occurred after click conjugation of biomolecules to PdBT. For the leachable cytotoxicity study, a two-tailed unpaired Student’s t test was used to compare the live control with each experimental condition. PicoGreen data and the supplemental accelerated degradation study were analyzed using one-way analysis of variance (ANOVA) with Tukey’s post hoc test. All tests were performed at α = 0.05.

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