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Mice were challenged with TC-1 and treated with the irradiation protocol and/or CTGF/E7 DNA vaccine as described above. Serum samples were collected at day (D) 7, D14, D21, D28, and D35 after tumor challenge. A direct ELISA method was used to detect HPV E7-specific antibodies in sera, as previously described.23
Copyright and License information: ©2017 The American Society of Gene and Cell Therapy.
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