Zongtian Tong
  • Department of Cell Biology, Center for Metabolism and Obesity Research, Johns Hopkins School of Medicine, USA
Research focus
  • Biochemistry
  • 3 Author merit


Ph.D., Department of Biology, University of Pennsylvania, 2008

Current position

She is a Postdoctoral Fellow in the School of Medicine at Johns Hopkins University. Her current research focuses on the identification of E3 ubiquitin ligase substrates.


  1. Stewart, E. V., Nwosu, C. C., Tong, Z., Roguev, A., Cummins, T. D., Kim, D. U., Hayles, J., Park, H. O., Hoe, K. L., Powell, D. W., Krogan, N. J. and Espenshade, P. J. (2011). Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex. Mol Cell 42(2): 160-171.
  2. Tong, Z., Gao, X. D., Howell, A. S., Bose, I., Lew, D. J. and Bi, E. (2007). Adjacent positioning of cellular structures enabled by a Cdc42 GTPase-activating protein-mediated zone of inhibition. J Cell Biol 179(7): 1375-1384.
  3. Gao, X. D., Sperber, L. M., Kane, S. A., Tong, Z., Tong, A. H., Boone, C. and Bi, E. (2007). Sequential and distinct roles of the cadherin domain-containing protein Axl2p in cell polarization in yeast cell cycle. Mol Biol Cell 18(7): 2542-2560.
  4. Iwase, M., Luo, J., Nagaraj, S., Longtine, M., Kim, H. B., Haarer, B. K., Caruso, C., Tong, Z., Pringle, J. R. and Bi, E. (2006). Role of a Cdc42p effector pathway in recruitment of the yeast septins to the presumptive bud site. Mol Biol Cell 17(3): 1110-1125.
3 Protocols published
Subcellular Fractionation Using Accudenz Gradient to Separate ER/Golgi in Yeast
Author:  Zongtian Tong, date: 01/20/2012, view: 15211, Q&A: 0
This protocol describes how to separate the endoplasmic reticulum (ER) and Golgi apparatus in yeast cells using a subcellular fractionation approach with an Accudenz gradient.
Spot Assay for Yeast
Author:  Zongtian Tong, date: 01/05/2012, view: 39575, Q&A: 3
This protocol can be used to compare the cell growth rate of yeast under different growth conditions. It involves the serial dilution and spotting of yeast colonies.
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