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Table 1 demonstrates the assessments to be performed at given time periods.

Timing of assessments

*Or the nearest time-point when ABG is available. Any additional available ABG result will also be collected and imputed to the nearest hourly time-point. Additional blood sampling will be avoided to reduce patient discomfort.

†The 24 hours variables will be collected till death or discharge, whichever is earlier. ABG will be collected where available.

NIV, non-invasive ventilation.

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