Identification of the DEGs between COPD and NSCLC

LZ Lemeng Zhang
JC Jianhua Chen
HY Hua Yang
CP Changqie Pan
HL Haitao Li
YL Yongzhong Luo
TC Tianli Cheng
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For GSE106899, based on the logCPM values, the DEGs between COPD and COPD with NSCLC were identified by the edgeR package. For GSE12472 and GSE12428, the classical Bayesian method provided by the limma package was used to analyze the DEGs 20 (Version 3.10.3, http://www.bioconductor.org/packages/2.9/bioc/html/limma.html). The Benjamini & Hochberg method was used to perform multiple test calibration on the p.value and logFC values of the above genes to obtain the corrected p value (adj.P.Value). The adj.P.Val<0.05 and |logFC|>0.585 were selected as the threshold for the following analysis.

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