Data extraction was independently conducted by two independent investigators (Zhang and Zhou). Any disagreement was resolved by another investigator (Qi Mei). A data extraction sheet based on the Cochrane Consumers and Communication Review Group’s data extraction template was utilized. The following details were extracted: (I) details of the study: first author, publication year, country of patients and sample size; (II) clinicopathological features: race, gender, tumour TNM stage, vascular invasion, lymphatic invasion, lymph node invasion, pleural metastasis, location of protein expression; (III) Survival analysis related features: the proportion and patient number of positive PDPN expression, cut-off standard for the definition of positive staining or staining intensity, follow-up time and survival data (OS and PFS). Two reviewers (Zhang and Zhou) collected the data independently from every eligible study. Any unclarity or lack of disagreement was resolve by discussion with a third reviewer until final consensus.
Do you have any questions about this protocol?
Post your question to gather feedback from the community. We will also invite the authors of this article to respond.