Subjects

CM Carlo A. Mallio
LM Laura Messina
MP Marco Parillo
GV Gianguido Lo Vullo
BZ Bruno Beomonte Zobel
PP Paul M. Parizel
CQ Carlo C. Quattrocchi
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We screened our in-house image database and selected a time span from January 2008 to June 2017. We identified a group of 59 consecutive patients who had undergone at least 5 intravenous GBCAs injections, each exclusively with 0.1 mmol/kg body weight of Omniscan, GE Healthcare (gadodiamide 0.5 mmol/ mL).

The exclusion criteria were: (1) empty sella; (2) previous neurosurgery; (3) abnormal renal function evaluated by calculating (Modification of Diet in Renal Disease study equation) the estimated glomerular filtration rate (GFR) from a blood sample obtained less than 3 months prior to the inclusion (GFR < 60 mL/min); (4) unsatisfactory images due to MR artifacts or absence of unenhanced sagittal T1 images; (5) presence of neoplastic lesions involving the pituitary gland.

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