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Within the platform, we support the run-time computation of cosine similarity (i.e. 1 - cosine distance) between the queried gene and all other genes. This provides a measure of expression similarity across cells and can be used to identify co-regulated and co-expressed genes. Specifically, to perform this computation, we construct a ‘gene expression vector’ for each gene G. This corresponds to the set of CP10K values for gene G in each individual cell from the selected populations in the selected study.
Copyright and License information: ©2020, Venkatakrishnan et al
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