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To identify alterations of gene expression profile following PON3 downregulation, microarray experiments and analyses were performed. The cDNA microarrays were constructed as previously described [37]. The threshold used to screen differentially expressed genes is fold change ≥ 1.5 and p-value ≤ 0.05. GO (http://geneontology.org/) and KEGG pathway (http://www.genome.jp/kegg/pathway.html) analyses were performed using the standard enrichment computation method and ranked by p-values [38].
Copyright and License information: ©2016 Cai et al.
This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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