Statistical analysis

PV Paula Verneri
CE Camila Vazquez Echegaray
CO Camila Oses
MS Martin Stortz
AG Alejandra Guberman
VL Valeria Levi
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Experimental results were expressed as means + SEM of at least three biological replicates. Statistical significance between groups was analyzed using Lineal Mixed Models (LMM) followed by comparisons between means using the Tukey test, when required. Differences were regarded as significant at p ≤ 0.01. Residuals fitted normal distribution and homogeneity of variance. Otherwise, transformation of data was applied in some cases to meet both assumptions.

Comparison between the parameters presented in Supplementary Fig. S9 was performed using randomly-selected subsets of each parameter at the nucleoplasm to generate data sets with similar sizes to that collected at foci. Statistical tests showed identical results with all the subsets.

Statistical analysis was performed using either Infostat58 or the gls package of RStudio.

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