Pharmacokinetic studies

GA Ghina Alameh
AE Agnès Emptoz-Bonneton
MR Marc Rolland de Ravel
EM Eva L. Matera
EM Elisabeth Mappus
PB Patrick Balaguer
LR Luc Rocheblave
TL Thierry Lomberget
CD Charles Dumontet
MB Marc Le Borgne
MP Michel Pugeat
CG Catherine Grenot
CC Claude Y. Cuilleron
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Plasmatic concentrations of doxorubicin were determined after ip injections of doxorubicin (10 mg/kg dissolved in 50 µL of physiological serum) alone or in the presence of steroid modulator 4 (20 mg/kg, dissolved in 200 µL of vehicle) to three female OF1 mice per time point (0.5, 1, 2, 4, 8 and 24 h) (Experimental Section in SI).

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