Plasmatic concentrations of doxorubicin were determined after ip injections of doxorubicin (10 mg/kg dissolved in 50 µL of physiological serum) alone or in the presence of steroid modulator 4 (20 mg/kg, dissolved in 200 µL of vehicle) to three female OF1 mice per time point (0.5, 1, 2, 4, 8 and 24 h) (Experimental Section in SI).
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