For all groups that were statistically compared, the variance between the groups was very similar. Comparisons between two groups were calculated using Student’s t-test (two tailed) and a P-value < 0.05 (*) was considered significant. Results are presented as means ± SD. Comparisons between more than two groups were calculated with one-way analysis of variance (ANOVA) followed by Bonferroni’s multiple comparison tests. To assess the number and the volume of tumors, a two-way ANOVA analysis of variance test followed by a post hoc Bonferroni’s test was used. A P-value < 0.05 (*) was considered significant. Results are presented as means ± SEM.
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