Data are expressed as mean ± standard error (SEM). Two-way repeated measures ANOVA was performed on mouse tumor volumes using GraphPad Prism 7.0 software, and CCK8 data were analyzed using one-way ANOVA with significance expressed as p values, with * p < 0.05 representing significant differences and ** p < 0.01 and *** p < 0.001 representing highly significant differences.
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