Unless otherwise stated in the figure legends, all the date were analyzed by using GraphPad Prism (9.0.0) software. The data are presented as the mean ± SEM from at least three independent experiments. ∗p < 0.05; ∗∗p < 0.01; ∗∗∗p < 0.001; ∗∗∗∗p < 0.0001 by Student’s t test for comparison.
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