Two researchers (XLX and QFS), independently evaluated the methodological quality of each reviewed study using the Cochrane Risk of Bias tools 2.0 (ROB 2.0) to assess the risk of bias in randomized trials. Any discrepancies between their assessments were resolved through discussion, or consultation with a third researcher (GQC) was sought if a consensus could not be reached. The methodological quality of the studies was assessed across several domains, including the randomization process, adherence to intended interventions, handling of missing outcome data, measurement of outcomes, and selection of reported results. Each of these domains was categorized as Low risk, High risk, or Some concerns according to the ROB 2.0 criteria.
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