When box graphs are plotted (Figs. 1d–g, 2c, e-g, 3c, e and supplementary Fig. 2v, 4k), the middle line represents the median value of the sample. The color box extremities represent the first and the third quartile of the whole sample (n). The mean of each independent replicate (N) is shown with larger points on the plot. All the data points (n) are shown with small and transparent points on the graphs, revealing the whole distribution of the sample. When scatter plots were plotted, values shown in the text and Figures are mean and standard deviation (SD). The number of independent measurements are indicated in captions of principal figures and the Source Data. When “N” is used, it refers to N different day of analysis. For all measurements of the physical properties of GOVs, each data point refers to GOVs extracted from independent cells. Size distributions are shown as frequency distributions by using GraphPad Prism software and the violin plot settings (Fig. 1b and supplementary Fig. 1m, p) or scatter plots (supplementary Fig. 1h, k, l, n, o).
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