The Y maze was a Y-shaped apparatus with three arms (30 cm long, 6 cm wide, and 15 cm high). The arms were at a 120° angle from each other. The test was performed in 2 phases: phase 1, with one of the lateral arms closed, and phase 2, with all three arms open. In phase 1, mice were randomly placed at the end of one of the 2 arms and allowed to explore for 3 min. Mice were again randomly placed at the end of one of the 3 arms of the maze 2 h following phase 1. In phase 2, the mazes’ three arms were open for exploration for 3 min. The indices were defined as follows: entries of novel arm exploration/(entries of novel arm exploration + entries of old arms exploration) × 100%; time of novel arm exploration/(time of novel arm exploration + time of old arms exploration) × 100%.
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