Since 2001, TBEV infections in humans have constituted a notifiable disease in Germany. Detailed case definitions—based on serological testing—are issued by the Robert-Koch Institute (RKI) and European Centre for Disease Prevention and Control (ECDC). It must be taken into consideration that the German case definition also includes all cases of laboratory-confirmed TBEV infection, independent of the clinical course. Case numbers are provided by the RKI via an online search tool, SurvStat (SurvStat 2.0), which offers open access.
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