Model discrimination

CW Chung Kwan Wong
BM Barbara C van Munster
AH Athanasios Hatseras
EV Else Huis in 't Veld
BL Barbara L van Leeuwen
SR Sophia E de Rooij
RP Rick G Pleijhuis
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Discrimination refers to the ability of the CPM to distinguish patients who develop delirium from those who do not develop delirium. Model discrimination is expressed as the area under the receiver operating characteristic curve, or ‘c-index’, which plots the sensitivity (true-positive rate) against 1−specificity (false-positive rate) for consecutive cut-offs of the predicted risk. Perfect discrimination gives a c-index of 1, and no discrimination (no better than the toss of a coin) results in a c-index of 0.50. Prediction models with c-indices between 0.9 and 0.99 are considered to have excellent discrimination, 0.8 and 0.89 good discrimination, 0.7 and 0.79 fair discrimination and 0.51 and 0.69 poor discrimination.11

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