Statistical analysis

Descriptive statistics were used for summarizing demographic, disease, and treatment characteristics. To compare nominal variables of baseline characteristics in different subgroups, the chi-square test was used. Student’s t-test or Mann–Whitney test was used for continuous variables, depending on data distribution. Overall survival was calculated from the time of diagnosis until death from any cause or last follow-up using the Kaplan–Meier method and differences were compared with the log-rank test. Leukemia-free survival was defined as the time from CR until relapse. A p value of < 0.05 was considered significant. Data were compiled using Microsoft Excel (Microsoft Corporation, Redmond, WA, USA), statistical analyses were performed using JMP version 14.0 (SAS Institute, Cary, NC, USA), and survival curves were plotted on Prism GraphPad version 8.4 (GraphPad Software Inc., La Jolla, CA, USA).