Correlation Analyses

Connectivity (mean between each seed and significant cluster) and topological metrics for each patient were tested with a Pearson’s correlation coefficient for relationships with symptoms (BPRS, SANS, GAF) and global functioning. Correlations with subscales (e.g. SANS Alogia) were only examined if a significant association was observed between the corresponding total score on a scale (e.g. SANS Total) and fMRI-related metrics. Due to the low sample size, we used a liberal significance threshold in which correlations with p < 0.05 were considered significant. These analyses should therefore be considered exploratory.