Regional practice and feature use

This registry aims to better understand regional differences in the implementation of VNS. Specifically, there is interest in identifying regional variances in clinical and safety outcomes associated with different implementations of VNS dosing and standard clinical practice. Newer models of VNS devices have only recently become available in some of the regions participating in the registry, so differences may be apparent in the use of new features. The features available in these newer models offer more programming flexibility and the potential for improved clinical and safety outcomes, but may also add complexity to the therapy. In this study, rationale for the selection of a Model 1000 ‘SenTiva’ generator is collected by ranking the relative importance of each feature in the eventual decision. The rationale options for device or feature selection include: scheduled programming, day/night programming, low heart rate detection, prone position detection, events and trends, availability of AutoStim with a smaller generator.