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Invasion & metastasis Microenvironment Oncogenesis Proliferative signaling Replicative immortality Tumor immunologyXenograft Tumor Growth Assay
Chronic inflammation drives initiation of hepatocellular carcinoma (HCC), but the underlying mechanisms linking inflammation and tumor formation remain obscure. In this study, Xenograft tumor assay was used to determine the tumorigenic activity of hepatoma cells with ISX over expression on nude mice in vivo.