联合作者(
Gopal P Sapkota Medical Research Council Protein Phosphorylation and Ubiquitylation Unit, UK, UK,
1 protocol

Thomas J Macartney Medical Research Council Protein Phosphorylation and Ubiquitylation Unit, UK, UK,
1 protocol

Luke J Fulcher
  • Graduate, Medical Research Council Protein Phosphorylation and Ubiquitylation Unit, UK, UK,
研究方向
  • 生物化学
  • 已发表 protocol 1

Education

BSc (Hons), University of Dundee, UK, 2015

Current position

PhD, MRC PPU, University of Dundee, UK

Publications

  1. Fulcher, L. J., Hutchinson, L. D., Macartney, T. J., Turnbull, C. and Sapkota, G. P. (2017). Targeting endogenous proteins for degradation through the affinity-directed protein missile system. Open Biol 7(5).
  2. Fulcher, L. J., Macartney, T., Bozatzi, P., Hornberger, A., Rojas-Fernandez, A. and Sapkota, G. P. (2016). An affinity-directed protein missile system for targeted proteolysis. Open Biol 6(10).
已发表 protocol 1篇
An Affinity-directed Protein Missile (AdPROM) System for Targeted Destruction of Endogenous Proteins
靶向破坏内源蛋白的亲和力定向蛋白导弹(AdPROM)系统

作者:Thomas J Macartney, Gopal P Sapkota and Luke J Fulcher日期:11/20/2017,浏览量:8020,Q&A: 0
We recently reported an Affinity-directed PROtein Missile (AdPROM) system for the targeted proteolysis of endogenous proteins of interest (POI) (Fulcher et al., 2016 and 2017). AdPROM consists of the Von Hippel Lindau (VHL) protein, a ...