联合作者(
James Shorter Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, USA
2 protocols

Emma Robinson Department of Biochemistry and Molecular Biology, Thomas Jefferson University, 2019-2020
1 protocol

Lin Guo
  • Assistant Professor, Biochemistry and Molecular Biology, Thomas Jefferson University, 2019-
研究方向
  • -
  • 已发表 protocol 1

教育背景

PhD, University of Pennsylvania, United States, 2011

发表论文

已发表 protocol 1篇
Karyopherin-β2 Inhibits and Reverses Aggregation and Liquid-liquid Phase Separation of the ALS/FTD-Associated Protein FUS
核转运蛋白-β2抑制和ALS / FTD相关蛋白FUS的逆转聚集和液-液相分离

作者:Emma Robinson, James Shorter and Lin Guo日期:08/20/2020,浏览量:2216,Q&A: 0
The study of RNA-binding proteins (RBP) offers insight into the mechanisms of pathologic protein aggregation in neurodegenerative diseases. We developed a protocol for purifying an RBP FUS and a nuclear import receptor (NIR) Kapβ2 and testing the ...