Education
Ph.D. in Physical Organic Chemistry, University of Chicago, 1968
Current position
SUNY Distinguished Professor, Biochemistry, Jacobs School of Medicine and Biomedical Sciences
Publications (since 2011)
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Bailao, E. F., Lima Pde, S., Silva-Bailao, M. G., Bailao, A. M., Fernandes Gda, R., Kosman, D. J. and Soares, C. M. (2015). Paracoccidioides spp. ferrous and ferric iron assimilation pathways. Front Microbiol 6: 821.
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Ji, C. and Kosman, D. J. (2015). Molecular mechanisms of non-transferrin-bound and transferring-bound iron uptake in primary hippocampal neurons. J Neurochem 133(5): 668-683.
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McCarthy, R. C. and Kosman, D. J. (2015). Mechanisms and regulation of iron trafficking across the capillary endothelial cells of the blood-brain barrier. Front Mol Neurosci 8: 31.
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McCarthy, R. C. and Kosman, D. J. (2015). Iron transport across the blood-brain barrier: development, neurovascular regulation and cerebral amyloid angiopathy. Cell Mol Life Sci 72(4): 709-727.
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McCarthy, R. C., Park, Y. H. and Kosman, D. J. (2014). sAPP modulates iron efflux from brain microvascular endothelial cells by stabilizing the ferrous iron exporter ferroportin. EMBO Rep 15(7): 809-815.
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McCarthy, R. C. and Kosman, D. J. (2014). Activation of C6 glioblastoma cell ceruloplasmin expression by neighboring human brain endothelia-derived interleukins in an in vitro blood-brain barrier model system. Cell Commun Signal 12: 65.
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McCarthy, R. C. and Kosman, D. J. (2014). Glial cell ceruloplasmin and hepcidin differentially regulate iron efflux from brain microvascular endothelial cells. PLoS One 9(2): e89003.
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Kjaergaard, C. H., Qayyum, M. F., Augustine, A. J., Ziegler, L., Kosman, D. J., Hodgson, K. O., Hedman, B. and Solomon, E. I. (2013). Modified reactivity toward O2 in first shell variants of Fet3p: geometric and electronic structure requirements for a functioning trinuclear copper cluster. Biochemistry 52(21): 3702-3711.
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McCarthy, R. C. and Kosman, D. J. (2013). Ferroportin and exocytoplasmic ferroxidase activity are required for brain microvascular endothelial cell iron efflux. J Biol Chem 288(24): 17932-17940.
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Kosman, D. J. (2013). Iron metabolism in aerobes: managing ferric iron hydrolysis and ferrous iron autoxidation. Coord Chem Rev 257(1): 210-217.
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McCarthy, R. C. and Kosman, D. J. (2012). Mechanistic analysis of iron accumulation by endothelial cells of the BBB. Biometals 25(4): 665-675.
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Kosman, D. J. (2011). Transport: Plutonium's Trojan horse. Nat Chem Biol 7(8): 498-499.
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Ziegler, L., Terzulli, A., Gaur, R., McCarthy, R. and Kosman, D. J. (2011). Functional characterization of the ferroxidase, permease high-affinity iron transport complex from Candida albicans. Mol Microbiol 81(2): 473-485.