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Frederic Boal
  • INSERM U1048 I2MC and Université Paul Sabatier, France
研究方向
  • Cancer biology
个人信息

Education

Ph.D, University of Bordeaux, France, 2006

Current position

Research Associate, Institute of Cardiovascular and Metabolic Diseases, INSERM, France

Publications

  1. Timotin, A., Pisarenko, O., Sidorova, M., Studneva, I., Shulzhenko, V., Palkeeva, M., Serebryakova, L., Molokoedov, A., Veselova, O., Cinato, M., Tronchere, H., Boal, F. and Kunduzova, O. (2017). Myocardial protection from ischemia/reperfusion injury by exogenous galanin fragment. Oncotarget.
  2. Boal, F., Timotin, A., Roumegoux, J., Alfarano, C., Calise, D., Anesia, R., Parini, A., Valet, P., Tronchere, H. and Kunduzova, O. (2016). Apelin-13 administration protects against ischaemia/reperfusion-mediated apoptosis through the FoxO1 pathway in high-fat diet-induced obesity. Br J Pharmacol 173(11): 1850-1863.
  3. Boal, F., Puhar, A., Xuereb, J. M., Kunduzova, O., Sansonetti, P. J., Payrastre, B. and Tronchere, H. (2016). PI5P Triggers ICAM-1 Degradation in Shigella Infected Cells, Thus Dampening Immune Cell Recruitment. Cell Rep 14(4): 750-759.
  4. Boal, F., Roumegoux, J., Alfarano, C., Timotin, A., Calise, D., Anesia, R., Drougard, A., Knauf, C., Lagente, C., Roncalli, J., Desmoulin, F., Tronchere, H., Valet, P., Parini, A. and Kunduzova, O. (2015). Apelin regulates FoxO3 translocation to mediate cardioprotective responses to myocardial injury and obesity. Sci Rep 5: 16104.
  5. Boal, F., Mansour, R., Gayral, M., Saland, E., Chicanne, G., Xuereb, J. M., Marcellin, M., Burlet-Schiltz, O., Sansonetti, P. J., Payrastre, B. and Tronchere, H. (2015). TOM1 is a PI5P effector involved in the regulation of endosomal maturation. J Cell Sci 128(4): 815-827.
  6. Boal, F., Hodgson, L. R., Reed, S. E., Yarwood, S. E., Just, V. J., Stephens, D. J., McCaffrey, M. W. and Tavare, J. M. (2016). Insulin promotes Rip11 accumulation at the plasma membrane by inhibiting a dynamin- and PI3-kinase-dependent, but Akt-independent, internalisation event. Cell Signal 28(1): 74-82.
  7. Viaud, J., Boal, F., Tronchere, H., Gaits-Iacovoni, F. and Payrastre, B. (2014). Phosphatidylinositol 5-phosphate: a nuclear stress lipid and a tuner of membranes and cytoskeleton dynamics. Bioessays 36(3): 260-272.
  8. Boal, F., Laguerre, M., Milochau, A., Lang, J. and Scotti, P. A. (2011). A charged prominence in the linker domain of the cysteine-string protein Cspalpha mediates its regulated interaction with the calcium sensor synaptotagmin 9 during exocytosis. FASEB J 25(1): 132-143.
  9. Guetzoyan, L. J., Spooner, R. A., Boal, F., Stephens, D. J., Lord, J. M., Roberts, L. M. and Clarkson, G. J. (2010). Fine tuning Exo2, a small molecule inhibitor of secretion and retrograde trafficking pathways in mammalian cells. Mol Biosyst 6(10): 2030-2038.
  10. Boal, F. and Stephens, D. J. (2010). Specific functions of BIG1 and BIG2 in endomembrane organization. PLoS One 5(3): e9898.
  11. Boal, F., Guetzoyan, L., Sessions, R. B., Zeghouf, M., Spooner, R. A., Lord, J. M., Cherfils, J., Clarkson, G. J., Roberts, L. M. and Stephens, D. J. (2010). LG186: An inhibitor of GBF1 function that causes Golgi disassembly in human and canine cells. Traffic 11(12): 1537-1551.
  12. Spooner, R. A., Watson, P., Smith, D. C., Boal, F., Amessou, M., Johannes, L., Clarkson, G. J., Lord, J. M., Stephens, D. J. and Roberts, L. M. (2008). The secretion inhibitor Exo2 perturbs trafficking of Shiga toxin between endosomes and the trans-Golgi network. Biochem J 414(3): 471-484.
  13. Boal, F., Le Pevelen, S., Cziepluch, C., Scotti, P. and Lang, J. (2007). Cysteine-string protein isoform beta (Cspbeta) is targeted to the trans-Golgi network as a non-palmitoylated CSP in clonal beta-cells. Biochim Biophys Acta 1773(2): 109-119.
  14. Monterrat, C., Boal, F., Grise, F., Hemar, A. and Lang, J. (2006). Synaptotagmin 8 is expressed both as a calcium-insensitive soluble and membrane protein in neurons, neuroendocrine and endocrine cells. Biochim Biophys Acta 1763(1): 73-81.
  15. Boal, F., Zhang, H., Tessier, C., Scotti, P. and Lang, J. (2004). The variable C-terminus of cysteine string proteins modulates exocytosis and protein-protein interactions. Biochemistry 43(51): 16212-16223.