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Determining the Relative Fitness Score of Mutant Viruses in a Population Using Illumina Paired-end Sequencing and Regression Analysis
Authors:
Hangfei Qi
,
C. Anders Olson
,
Nicholas C. Wu
,
Yushen Du
and
Ren Sun
,
date:
05/20/2015,
view:
7996,
Q&A:
0
[Abstract] Recent advances in DNA sequencing capacity to accurately quantify the copy number of individual variants in a large and diverse population allows in parallel determination of the phenotypic effects caused by each genetic modification. This systematic profiling approach is a combination of forward and reverse genetics, which we refer to as ...
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