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Quantifying Symmetrically Methylated H4R3 on the Kaposi’s Sarcoma-associated Herpesvirus (KSHV) Genome by ChIP-Seq
Authors:
Roxanne C. Strahan
,
Kayla S. Hiura
and
Subhash C. Verma
,
date:
03/20/2018,
view:
6101,
Q&A:
0
[Abstract] Post-translational modifications to histone tails contribute to the three-dimensional structure of chromatin and play an important role in determining the relative expression of nearby genes. One such modification is symmetric di-methylation of arginine residues, which may exhibit different effects on gene expression including blocking the binding ...
Bioinformatic Analysis for Profiling Drug-induced Chromatin Modification Landscapes in Mouse Brain Using ChlP-seq Data
Authors:
Yong-Hwee Eddie Loh
,
Jian Feng
,
Eric Nestler
and
Li Shen
,
date:
02/05/2017,
view:
9693,
Q&A:
0
[Abstract] Chromatin immunoprecipitation followed by massively parallel sequencing (ChIP-seq) is a powerful technology to profile genome-wide chromatin modification patterns and is increasingly being used to study the molecular mechanisms of brain diseases such as drug addiction. This protocol discusses the typical procedures involved in ChIP-seq data ...
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