Senescence Associated β-galactosidase Staining
Authors: Michael Eccles and
Caiyun Grace Li,
date: 08/20/2012,
view: 64522,
Q&A: 17
[Abstract] Detection of senescent cells using a cytochemical assay was first described in 1995 (Dimri et al., 1995). The identification of senescent cells is based on an increased level of lysosomal β-galactosidase activity (Kurz et al., 2000). Cells under normal growth condition produce acid lysosomal β- galactosidase, which is localized ...