Myeloid Progenitor Transformation Assay
Authors: Hiroshi Okuda and
Akihiko Yokoyama,
date: 12/05/2017,
view: 6481,
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[Abstract] Numerous oncogenes have been identified to cause leukemia. For example, chromosomal translocation generates various fusion genes of the mixed-lineage leukemia (MLL) gene and a partner gene in leukemia, whose gene products transform primary myeloid progenitors into an immortalized state. To characterize the transforming ability of leukemic ...